Product ID:FUNGIZONE INTRAVENOUS OR POLYENE ANIFUNGAL ANTIBIOTIC
MSDS Date:11/23/1992
FSC:6840
NIIN:00D010009
MSDS Number: BTJSK

BRISTOL-MYERS SQUIBB PHARMACEUTICAL GROUP

NEW BRUNSWICK, NJ 08903
US

Emergency Phone: 908-519-2385(CHEMTREC 800-424-9300)

Info Phone: 609-243-6102

Cage: BRIST

BRISTOL-MYERS SQUIBB PHARMACEUTICAL GROUP

191 NEW BRUNSWICK, NJ 08903 US

Telephone: 908-519-2385

Cage: BRIST

AMPHOTERICIN B

CAS: 1397-89-3

RTECS: BU2625000

Fraction By Weight: 45%

SODIUM DESOXYCHOLATE

Fraction By Weight: >1%

SODIUM PHOSPHATE, DIBASIC (SARA III)

CAS: 7558-79-4

RTECS: WC4500000

Fraction By Weight: >1%

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

SODIUM PHOSPHATE, TRIBASIC (SARA III)

CAS: 7601-54-9

RTECS: TC9490000

Fraction By Weight: >1%

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

SODIUM HYDROXIDE (SARA III)

CAS: 1310-73-2

RTECS: WB4900000

Fraction By Weight: <1%

OSHA PEL 2 MG/M3

ACGIH TLV: C 2 MG/M3; 9394

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

PHOSPHORIC ACID (SARA III)

CAS: 7664-38-2

RTECS: TB6300000

Fraction By Weight: <1%

OSHA PEL 1 MG/M3

ACGIH TLV: 1 MG/M3/3 STEL; 9394

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

LD50 LC50 Mixture:ORAL LD50 (RAT) IS >5000 MG/KG
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: INJECTION OF PRODUCT MAY CAUSE
KIDNEY, LIVER, AND SYSTEMIC EFFECTS. RARELY ANAPHYLACTOID
REACTIONS, WHICH INVOLVE DIFFICULTY IN BREATHING AND MAY BE FATAL,
HAVE OCURRED. CHRONIC: NONE SPECIFIED BY MANUFACTURER.
Explanation of Carcinogenicity:NO INGREDIENTS OF A CONCENTRATION OF
0.1% OR GREATER IS LISTED AS A CARCINOGEN OR SUSPECTED CARCINOGEN.
Effects of Overexposure:FEVER, SWEATING, SHAKING CHILLS, HEADACHE, LOSS
OF APPETITE, WEIGHT LOSS, NAUSEA, VOMITING, DIARRHEA, DYSPEPSIA,
MALAISE, MUSCLE AND JOINT PAIN, ABDOMINAL PAIN, PAIN AT INJECTION
SITE.
Medical Cond Aggravated by Exposure:WHEN THIS MATERIAL IS INJECTED
INTERVENOUSLY IT MAY AGGRAVATE CERTAIN KIDNEY DISORDERS.

First Aid:INHALED: REMOVE TO FRESH AIR. GIVE OXYGEN IF BREATHING
DIFFICULT. GIVE ARTIFICIAL RESPIRATION IF BREATHING STOPPED. GET
IMMEDIATE MEDICAL ATTENTION. EYES: FLUSH WITH LOTS OF WATER FOR
15-20 MINUTES. S KIN: WASH WITH SOAP AND WATER. INGESTED: IF
CONSCIOUS, INDUCE VOMITING. GET MEDICAL ATTENTION. HMIS-TARGET
ORGANS: KIDNEYS, LIVER.

Flash Point:NOT AVAILABLE
Extinguishing Media:WATER
Fire Fighting Procedures:WEAR SELF-CONTAINED BREATHING APPARATUS AND
FULL BUNKER GEAR. USE WATER TO COOL FIRE EXPOSED CONTAINERS. DIVERT
RUN-OFF TO SAFE AREA.
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

Spill Release Procedures:WEAR PROPER PROTECTIVE CLOTHING (AS A
MINIMUM-LATEX GLOVES, EYE PROTECTION, NIOSH/MSHA APPROVED
RESPIRATOR W/HEPA FILTER) . SWEEP ONTO PAPER & PLACE INTO AN
APPROPRIATE FIBER DRUM FOR DISPOSAL. VENTIL ATE AND DECONTAMINATE
AFTER MATERIAL ISPICKED UP.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE REFRIGERATED (LESS THAN 5C).
PROTECT FROM LIGHT.
Other Precautions:THERAPEUTIC AGENTS ARE INTENDED FOR USE UNDER
DIRECTION OF A PHYSICIAN AND/OR UNDER THE CONDITIONS OF USE
DESCRIBED ON THE LABEL. AS A GENERAL PRECAUTION, PERSONNEL WHO
HANDLE DRUG SUBSTANCES SHOULD A VOID CONTACT WITH THESE SUBSTANCES.

Respiratory Protection:IF ENGINEERING CONTROLS FAIL OR EMERGENCY
OCCURS; USE NIOSH/MSHA APPROVED RESPIRATOR OR SELF-CONTAINED
BREATHING APPARATUS, AS REQUIRED. USE IN ACCORDANCE WITH 29 CFR
1910.134.
Ventilation:USE ADEQUATE MECHANICAL VENTILATION WITH HEPA FILTRATION TO
MAINTAIN EXPOSURE BELOW TLV.
Protective Gloves:RUBBER, LATEX
Eye Protection:SAFETY GLASSES WITH SIDE SHIELDS.
Other Protective Equipment:LAB COAT OR GOWN. HMIS-EYE WASH STATION &
SAFETY SHOWER AVAILABLE.
Work Hygienic Practices:WASH HANDS AFTER USE AND BEFORE EATING,
DRINKING, OR SMOKING. LAUNDER CONTAMINATED CLOTHES BEFORE REUSE.
Supplemental Safety and Health

HCC:T6
Solubility in Water:APPRECIABLE
Appearance and Odor:VIALS CONTAINING LIGHT YELLOW TO ORANGE LYOPHILIZED
POWDER OR CAKE; ODORLESS.

Stability Indicator/Materials to Avoid:YES
NONE KNOWN
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE,
OXIDES OF NITROGEN.

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE WITH LOCAL, STATE AND
FEDERAL REGULATIONS OR THE REGULATIONS OF THE COUNTRY IN WHICH IT
IS USED.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.